Role within the CfCWR
Mr Barton is the trial management and team lead of the Diagnostics, Drugs, Devices and biomarkers (D3B) team which will support the anti-scarring dressing clinical trial.
D3B clinical trial team, Institute of Translational Medicine, Birmingham.
Mr Barton Joined CRCTU in July 2002 as a trial administrator, working in the field of urology (Prostate cancer and Bladder cancer). In 2005 Darren was promoted to Trial coordinator and his first investigator-led study was: TRAPEZE a phase II/III randomised study combine strontium-89, Zoledronic acid and docetaxel chemotherapy in patients with advanced metastatic prostate cancer involving the bone.
Darren has subsequently coordinated (National coordinator and Local coordinator) a number of academic Phase I, II clinical trials involving medical devices, Investigational Medicinal Products (IMPs), Advanced therapy investigational products (ATIMPs) In the field of liver disease. The majority of which were after he was promoted to senior trial coordinator (2009) and he was one of the first appointees to the new NIHR Liver Biomedical research unit Founded in August 2009. Darren was responsible along with other senior member of the team for managing a wide portfolio of industry-sponsored liver trials (HCV, Auto-immune disease, liver transplantation, NASH) as well as the coordinator for Multiple investigator-led academic/industry collaboration Phase I/II trials in Liver cirrhosis, Non-alcoholic fatty liver disease, and Hepatitis C reinfection (post-transplant- prevention). This studies involved IMPs, Biological therapy and medical devices. He has worked closely with industry and various clinical teams at the Queen Elizabeth hospital and has run trials on behalf of the University of Birmingham (sponsor).
In 2016 Darren was appointed a D3B Trials team leader and currently leads the new D3B team portfolio. D3B is a core member of the Birmingham Health partners ITM initiative: https://www.birminghamhealthpartners.co.uk/research/institute-of-translational-medicine/
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